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r t u n i t i e s + i n + o t h e r + t h e r a p e u t i c + a r e a s + t o + t h e + e x t e n t + t h e y + a r i s e + t h r o u g h + a c q u i s i t i o n s + + s h i r e % 2 7 s + i n - l i c e n s i n g % 2 c + m e r g e r + a n d + a c q u i s i t i o n + e f f o r t s + a r e + f o c u s e d + o n + p r o d u c t s + i n + s p e c i a l i s t + m a r k e t s + w i t h + s t r o n g + i n t e l l e c t u a l + p r o p e r t y + p r o t e c t i o n + a n d + g l o b a l + r i g h t s + + s h i r e + b e l i e v e s + t h a t + a + c a r e f u l l y + s e l e c t e d + a n d + b a l a n c e d + p o r t f o l i o + o f + p r o d u c t s + w i t h + s t r a t e g i c a l l y + a l i g n e d + a n d + r e l a t i v e l y + s m a l l - s c a l e + s a l e s + f o r c e s + w i l l + d e l i v e r + s t r o n g + r e s u l t s % 0 a % 0 d % 0 a % 0 d % 0 a + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + % 0 d % 0 a + + + + + + + + + + + + + + + + + + + + + + + + + + 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s + a r e + f o r w a r d - l o o k i n g + s t a t e m e n t s + s u c h + f o r w a r d - l o o k i n g + s t a t e m e n t s + i n v o l v e + a + n u m b e r + o f + r i s k s + a n d + u n c e r t a i n t i e s + a n d + a r e + s u b j e c t + t o + c h a n g e + a t + a n y + t i m e + i n + t h e + e v e n t + s u c h + r i s k s + o r + u n c e r t a i n t i e s + m a t e r i a l i z e % 2 c + t h e + c o m p a n y % 2 7 s + r e s u l t s + c o u l d + b e + m a t e r i a l l y + a d v e r s e l y + a f f e c t e d + t h e + r i s k s + a n d + u n c e r t a i n t i e s + i n c l u d e % 2 c + b u t + a r e + n o t + l i m i t e d + t o % 2 c + r i s k s + a s s o c i a t e d + w i t h % 3 a + t h e + i n h e r e n t + u n c e r t a i n t y + o f + r e s e a r c h % 2 c + d e v e l o p m e n t % 2 c + a p p r o v a l % 2 c + r e i m b u r s e m e n t % 2 c + m a n u f a c t u r i n g + a n d + c o m m e r c i a l i z a t i o n + o f + t h e + c o m p a n y % 2 7 s + s p e c i 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