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FDA-mandated labeling change for simvastatin regarding risk of higher dosages. PDF Print
MedWatch: RECOMMENDATION: Simvastatin 80 mg should not be started in new patients, including patients already taking lower doses of the drug.

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Pretreatment of mice with thymosin beta 4 induces cardiac repair after induced infarct. PDF Print
BBC: The damage caused by a heart attack had previously been considered permanent. But a study in the journal Nature showed the drug, thymosin beta 4, if used in advance of a heart attack, was able to "prime" the heart for repair.

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SHARP trial (simvastatin plus ezetimibe in CKD) results published in the Lancet. PDF Print
Lancet: Interpretation - Reduction of LDL cholesterol with simvastatin 20 mg plus ezetimibe 10 mg daily safely reduced the incidence of major atherosclerotic events in a wide range of patients with advanced chronic kidney disease.

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How to save a life - Reportage Online PDF Print
Reportage Online
Saleh never expected to get one, and resigned himself to a lifetime on dialysis. He started doing dialysis three times a week for six hours each time and after suffering a heart attack, this increased to four times a week. “I remember my first niece

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FDA: Myopathy risk of high-dose (80 mg) simvastatin close to 50%; limitations to use recommended. PDF Print
AHA: The United States Food and Drug Administration (FDA) today announced new limitations to the use of high-dose simvastatin, due to the increased risk of muscle pain and weakness (myopathy) and in rare cases, kidney damage and failure.

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