Dialysis world news


Medtronic to launch new phase II trial of renal nerve ablation (Symplicity device)
St. Paul / Minneapolis Business Journal: Medtronic Inc.'s Symplicity system, designed to treat high blood pressure in patients, took a blow last year when it flubbed a clinical trial. But the company is poised to launch another trial this year.

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Dabigatran has higher bleeding risk than warfarin in dialysis patients
Healio.com (Circulation): "Our study is the first to evaluate these drugs in the dialysis population, and suggests concern given the increasing use of dabigatran and rivaroxaban in the ESRD population despite formal FDA warnings of caution in renal failure," the researchers wrote. "In fact, our secondary analyses suggest excess morbidity and mortality from bleeding are associatively higher with dabigatran and rivaroxaban when compared to warfarin."

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Blue-green algae (cyanobacteria) proliferating in lakes worldwide.
McGill University: The organisms commonly known as blue-green algae have proliferated much more rapidly than other algae in lakes across North America and Europe over the past two centuries - and in many cases the rate of increase has sharply accelerated since the mid-20th century, according to an international team of researchers led by scientists at McGill University.

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Polysorbate 80 and carboxymethylcellulose - food emulsifiers, and metabolic syndrome
EurekAlert: Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can alter the gut microbiota composition and localization to induce intestinal inflammation that promotes the development of inflammatory bowel disease and metabolic syndrome, new research shows.

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AKI electronic alert system backfires and increases interventions without improving outcomes.
Yale University: While the alert system did not improve outcomes, in a subset of patients it did increase interventions, including more renal consultations and dialysis. These interventions, however, did not correlate with higher-quality care. “For acute kidney injury, more treatment is not necessarily better,” Wilson noted.

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