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Antibiotics Linked to Higher Risk of Diabetes - Renal and Urology News
March 30, 2015 Antibiotics Linked to Higher Risk of Diabetes - Renal and Urology News
Data on 1 million people suggest a higher risk of the illness linked to changes in gut microbes.

(HealthDay News) -- Repeated use of certain antibiotics may increase a person's risk for type 2 diabetes, new research suggests. The study was published online in the European Journal of Endocrinology.

Researchers analyzed data from 1 million people in the United Kingdom and found that those who were prescribed at least 2 courses of 4 types of antibiotics -- penicillins, cephalosporins, quinolones, and macrolides -- were more likely to develop diabetes. The risk of diabetes rose with the number of antibiotics prescribed.

2 to 5 courses of a penicillin increased the risk of diabetes by 8%, while more than 5 courses increased the risk by 23%. 2 to 5 courses of quinolones increased the risk of diabetes by 15% percent, and more than 5 courses increased the risk by 37%, the researchers found. The higher risk of diabetes associated with the antibiotics was determined after adjusting for other diabetes risk factors such as obesity, smoking, coronary artery disease, and infections.

"While our study does not show cause and effect, we think changing levels and diversity of gut bacteria could explain the link between antibiotics and diabetes risk," senior author Yu-Xiao Yang, M.D., of the University of Pennsylvania in Philadelphia, said in a journal news release. Lead author Ben Boursi, M.D., of the Mount Sinai Beth Israel Hospital in New York City, told HealthDay that "gut bacteria have been suggested to influence the mechanisms behind obesity, insulin resistance and diabetes in both animal and human models. Previous studies have shown that antibiotics can alter the digestive ecosystem."

Source

  1. Boursi, B, et al. Published online before print by Eur J Endocrinol, March 24, 2015; doi: 10.1530/EJE-14-1163.

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Lakeridge Health receives $1.2 million for dialysis machines from community ... - durhamregion.com

OSHAWA -- Oshawa resident John Mash knows first-hand how a $1.2-million donation for new dialysis machines at Lakeridge Health will help people in the community.

He was on hand at a recent announcement by the Lakeridge Health Foundation that the dollars from the kidney dialysis campaign will be donated to Lakeridge Health for the purchase of 46 new kidney dialysis machines, including 18 machines for home use.

Ten years ago, Mr. Mash began undergoing dialysis due to kidney failure brought on by diabetes he had grappled with since he was 25 years old. He had progressively gotten sicker and sicker. As his kidney functioned dropped to between 12 and 15 per cent, just walking across a room became a challenge.

With the dialysis he could restore some of his energy.

“Anywhere between 35 and 40 hours a week I felt good,” said the 62-year-old. “You do it because you want to be healthy, I was able to get out walking more.”

In 2009, Mr. Mash received a kidney transplant from his niece, a gift so generous he still struggles to understand why she did it.

“She said my kids don’t have a grandfather so you’re going to be a grandfather for them.”

Now he shares his story to support Lakeridge Health where he says he received top-notch care.

“I’ll always tell my story. It’s an amazing thing I’m surrounded by heroes, my wife, my niece, the people at the hospital.”

The typical lifespan of a dialysis machine is five to 10 years, depending on how many hours it’s used, and each machine costs roughly $25,000. The Lakeridge Health Foundation has made replacing the hospital’s 87 aging dialysis machines one of its top fundraising priorities.

“The Province pays for the operating cost of health care and our hospitals and the reason why hospital foundations exist is to raise money for capital projects and equipment,” said Bob Baker, the Lakeridge Health Foundation’s former CEO.

Over the last three years the foundation has donated more than $4 million to Lakeridge Health towards the purchase of equipment, including funding toward a new CT suite, ultrasound machines, a portable breast specimen X-ray machine, dialysis machines and new hospital beds.

In 2013-14 the Lakeridge Health Foundation received a total of $5.28 million from 8,500 donors. That included two of the largest donations ever received by the foundation: $325,000 from the RBC Foundation for mental health programs in Durham and $2 million from a life-long Brooklin resident designated for complex continuing care.

Dollars come to the foundation in numerous ways, from the organization’s marquee large fundraisers such as the annual gala and golf tournament, corporate donations, donations designated in wills, and small fundraisers held within the community to benefit the hospital.

When the Province does contribute money for capital expenses, Lakeridge executive vice-president Tom McHugh explained that there’s often an expectation that the local community pitch in as well, citing the Durham Regional Cancer Centre as an example where the government provided funding but the community made a large contribution.

The foundation works with the hospital to determine where the funding should go.

“Two years ago in our discussions with the hospital around their key priorities for medical equipment, they identified they needed to replaces 87 dialysis machines,” explains Mr. Baker.

“We have good processes internally where we prioritize what we need, it’s not just put it on a list and we’ll get it, it’s really weighing the benefits of new technology, what are the things in highest need of replacement,” added Mr. McHugh.

As technology improves, patients receive better care. The dialysis machines in particular are essential to the hospital.

“They are the lifeline for these patients, as high-tech equipment goes,” explains Mr. McHugh. “Without out it, the impurities in their blood would build up and they would die; it’s a pretty modest amount of money for such lifesaving treatment.”

When people like Mr. Mash share their story, it’s a direct connection to the community.

“This donation represents hundreds of donors and they go out and tell this story to our community and the community in turn is generous in their donations,” said Mr. McHugh.

“Anytime someone can help out even if it’s a small way, it’s a positive way,” said Mr. Mash. “I’m amazed at the funds made available from people in our community helping people in need.”

KIDNEY DIALYSIS AT LAKERIDGE HEALTH

Hemodialysis at the hospital

• At any time there are between 270 and 275 patients

• The hospital has 62 machines between the Oshawa and Whitby sites

• The two sites deliver approximately 40,000 treatments a year

Home Dialysis

• Lakeridge currently has 45 home hemodialysis patients and 85 peritoneal dialysis patients

• Each year, the staff train 12 new home dialysis patients a year

HOW THIS IMPACTS YOU:

• Local hospitals rely on community donations for the purchase of new life-saving equipment

• A $1.2-million donation from the Lakeridge Health Foundation is replacing 46 aging kidney dialysis machines

• Lakeridge Health delivers more than 40,000 dialysis treatments each year in hospital and is the third-largest home dialysis provider in Ontario

• Kidney disease rates are expected to increase as it’s linked to both diabetes and aging

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Spike in Hypertension-Related Deaths, Says CDC - Renal and Urology News
March 30, 2015 Spike in Hypertension-Related Deaths, Says CDC - Renal and Urology News
Most marked increases in hypertension deaths seen in those aged 45 to 64 and those over 85.

(HealthDay News) -- The overall death rate from hypertension in the United States has increased 23% since 2000, even as the death rate from all other causes has dropped 21%, according to a March data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

The spike was seen in both genders and was most marked among those aged 45 to 64 and those over 85. "The age-adjusted deaths from high blood pressure went up, while the other causes of death went down," report coauthor Hsiang-Ching Kung, Ph.D., a statistician with the NCHS, told HealthDay.

From 2000 through 2013, the death rate from hypertension rose 58.2% for men aged 45 to 64 and increased 36.8% for women aged 45 to 64. Those aged 85 and older were also not spared, with men seeing a 27.5% increase in the death rate from hypertension between 2000 and 2005, while women saw an increase of 23% in that same period. Between 2005 and 2013, those rates continued to increase, but more slowly, the researchers found.

Kung and coauthor Jiaquan Xu, M.D., a CDC epidemiologist, also found that deaths related to hypertension varied by race. The death rate increased among Hispanics between 2000 and 2005. Since then, the death rate increased for whites but decreased among blacks, the researchers found. Although the overall number of deaths related to hypertension was still higher among blacks than among whites and Hispanics, the gap between them narrowed. "The disparity is narrowing, but more studies are needed to see why that's the case," Kung said.

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Case report: lupus nephritis with autoantibodies to complement alternative ... - BMC Blogs Network

1 Immunology Unit, University Hospital La Paz, IdiPAZ, Madrid, Spain

2 Unit 754, Center for Biomedical Research on Rare Diseases (CIBERER), Madrid, Spain

3 Department of Nephrology, University Hospital La Paz, IdiPAZ, Madrid, Spain

4 Department of Pathological Anatomy, University Hospital, IdiPAZ, Madrid, Spain

5 Immunology Unit, University Hospital La Paz, IdiPAZ, Madrid, Spain

6 Biological Research Center, CSIC, Madrid, Spain

7 Unit 738, Center for Biomedical Research on Rare Diseases (CIBERER), Madrid, Spain

8 Unidad de Inmunología, Hospital Universitario La Paz, IdiPAZ, Paseo de la Castellana, 261, Madrid, 28046, Spain

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Seha opens new paediatric dialysis unit - The National

ABU DHABI // A new paediatric dialysis unit has been opened by Seha, the Abu Dhabi Health Services Company, at Sheikh Khalifa Medical City in the capital.

Dr Zubaida Al Ismaili, deputy chief executive at Seha Dialysis Services, said the new paediatric dialysis unit comprised nine dialysis stations with a capacity of 27 patients a day. The unit provides four dialysis sessions a week for each child, with each session lasting about four hours.

Similar units have been planned for the Mafraq Dialysis Centre in Abu Dhabi and Tawam Hospital in Al Ain, and would bring the total capacity of the three centres to 204 dialysis units.

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