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Auto and bus windshield washer fluid found to be a source of Legionnaire's disease. |
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EurekAlert: A form of bacteria responsible for respiratory illness, including the deadly pneumonia known as Legionnaire's disease, may be able to grow in windshield washer fluid and was isolated from nearly 75% of school buses tested in one district in Arizona, according to research presented today at the annual meeting of the American Society for Microbiology. "Washer fluid spray can release potentially dangerous numbers of these bacteria into the air. These results suggest that automobiles may serve as a source of transmission for Legionella infections," says Otto Schwake, a doctoral student at Arizona State University, who presented the research.
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Benzodiazepine use for sleep markedly increase adverse events n heart failure patients. |
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EurekAlert: ... He (Dr. Steoguchi) added: "Benzodiazepine hyptonics may have cardiodepressant actions. They may also exert respiratory depressant actions which could exacerbate sleep disordered breathing and lead to a worse prognosis." Dr Setoguchi concluded: "Our results need confirmation in larger, prospective studies before heart failure patients can be advised to stop taking sleeping pills. But HFpEF patients who use sleeping pills, particularly those who have sleep disordered breathing, should be carefully monitored."
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Kallikrein inhibitor ecallantide shows some benefit in ACEI-associated angioedema. |
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University of Cincinnati: They wanted to see if Ecallantide, which has already safely treated acute attacks of hereditary angioedema, could help patients with ACEI angioedema—specifically, if it could make them eligible for discharge within four hours of treatment. After enrolling 50 patients in the study, they found that patients treated with Ecallantide were more likely to meet discharge sooner than those receiving antihistamines and steroids—31 percent of Ecallantide patients were eligible for discharge within four hours, as compared with 21 percent of patients receiving placebos. Additionally, patients experienced few side effects from the medication.
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T cells targeting CS1 kill myeloma cells in animals. |
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Ohio State University: The researchers modified a type of human immune cell – called T lymphocytes, or T cells – to target a molecule called CS1, which is found on more than 95 percent of myeloma cells, and to kill the cells. The researchers grew the modified cells in the lab to increase their numbers and then injected them into an animal model where they again killed human myeloma cells. The findings were published in the journal Clinical Cancer Research.
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Aspirin retards wound healing |
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EurekAlert: In addition to its known capacity to promote bleeding events, aspirin also inhibits wound healing. New research published in The Journal of Experimental Medicine now describes how aspirin acts on key skin cells called keratinocytes, delaying skin repair at wound sites. A better understanding of this process offers hope for the development of drugs to encourage wounds to heal.
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