Dialysis world news


Rhabdomyolysis in cross fit training participants.
Huffpo: A quick search of the Interwebs reveals copious amounts of information about rhabdo purveyed by none other than CrossFit trainers. Scouring the scientific literature in mainstream medical journals, however, reveals a only a few peer-reviewed papers.

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Melatonin stimulates brown fat formation.
Science Daily: The study -- coordinated by University of Granada lecturer Ahmad Agil -- showed that chronic administration of melatonin sensitizes the thermogenic effect of exposure to cold, heightens the thermogenic effect of exercise and, therefore, constitutes excellent therapy against obesity. The fact is that one of the key differences between 'beige fat', which appears when administering melatonin, and 'white fat', is that 'beige fat' cell mitochondria express levels of UCP1 protein, responsible for burning calories and generating heat.

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Remote ischemic conditioning using blood pressure cuff in acute heart attack
Science Daily: In patients with an acute heart attack, remote ischemic conditioning – intermittent inflation of a blood pressure cuff to cut off blood flow to the arm during transportation to hospital for acute balloon dilatation – reduces subsequent cardiac symptoms and mortality after acute heart attack. The results are presented by researchers from Aarhus University Hospital and Aarhus University in European Heart Journal on-line 12 September 2013.

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A mechanism to kill tuberculosis bacteria has been discovered.
Brown University: In a series of laboratory experiments, the researchers have shown that it is possible to kill Mycobacterium tuberculosis by inhibiting ClpP, a cellular enzyme that is not targeted by any antibacterial drug on the market. The work is preliminary, but the researchers are hopeful it could point the way to new drugs to treat tuberculosis and other infections that are becoming resistant to traditional antibiotics.

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Arginine therapy may be useful to treat sickle cell disease related pain.
Emory U: Arginine therapy may be a safe and inexpensive treatment for acute pain episodes in patients with sickle cell disease, according to results of a recent clinical study. The study was the first randomized placebo-controlled study to demonstrate benefits of arginine therapy in children with sickle cell disease hospitalized for severe pain.

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