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Peritonitis Ups Odds of Mortality in Peritoneal Dialysis Patients - Doctors Lounge
Among patients who die while on peritoneal dialysis, peritonitis is associated with mortality, with the highest odds for peritonitis in the 30 days before death, according to a study published online May 24 in the Journal of the American Society of Nephrology.

FRIDAY, May 25 (HealthDay News) -- Among patients who die while on peritoneal dialysis, peritonitis is associated with mortality, with the highest odds for peritonitis in the 30 days before death, according to a study published online May 24 in the Journal of the American Society of Nephrology.

Neil Boudville, M.D., from the Australia and New Zealand Dialysis and Transplant Registry in Adelaide, and colleagues conducted a case-crossover study involving 1,316 patients (mean age, 70 years) who received peritoneal dialysis (mean duration, three years) and either died on peritoneal dialysis or within 30 days of transfer to hemodialysis. Each patient served as his or her own control.

The researchers identified 1,446 reported episodes of peritonitis, with 27 percent of patients having two or more episodes. There were significantly increased odds of peritonitis during the 120 days before death compared to during the rest of the year, and the magnitude of this association was even greater during the 30 days before death. The odds for peritonitis was six-fold higher during the 30 days immediately before death (odds ratio, 6.2) compared with a 30-day window six months before death.

"Peritonitis significantly associates with mortality in peritoneal dialysis patients," the authors write. "The increased odds extend up to 120 days after an episode of peritonitis but the magnitude is greater during the initial 30 days."

Several authors disclosed financial ties to the health care and pharmaceutical industries.

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Obesity Ups Kidney Injury in Heart Surgery - MedPage Today
MedPage Today
While other research has found that obesity increases oxidative stress, endothelial dysfunction, and inflammation, the link to acute kidney injury was unclear, Billings and co-authors wrote online in JASN (Journal of the American Society of Nephrology)

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BHS selects Avera for operating dialysis unit - Brookings Register
Brookings Register
BROOKINGS – Avera McKennan Hospital and University Health Center of Sioux Falls will take over management of the Brookings dialysis unit, it was formally announced Wednesday by Jason Merkley, president and chief executive officer of Brookings Health

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Pfizer says EU recommends approval of Inlyta - BusinessWeek

NEW YORK

Pfizer Inc. said Friday that European Union regulators are recommending approval for its kidney cancer drug Inlyta.

A European Union advisory committee recommended that Inlyta be approved as a treatment for advanced renal cell carcinoma in patients who were not helped by treatment with Pfizer's drug Sutent or with cytokines, a class of cancer medications that are no longer widely used in the U.S. and Europe, the company said.

The drugmaker said the panel recommended approving the drug for use only in adults.

Renal cell carcinoma is the most common form of kidney cancer.

Inlyta, or axitinib, is a twice-per-day cancer pill. The Food and Drug Administration approved it in January as a secondary option for renal cell carcinoma.

Shares of Pfizer rose 11 cents to $22.25 in morning trading, approaching their 52-week high of $23.30 set late last month. Its shares are up from a low for the past year of $16.63 in early August.


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DPC Announces New President of the Board of Directors - Renal Business Today

WASHINGTON—Dialysis Patient Citizens (DPC) is proud to announce Eric Edwards has been named president of the DPC board of directors. Edwards, a longtime advocate for kidney disease patients, has been a DPC board member since 2010.

"I am honored and excited to take on this new opportunity. I have always felt my purpose on Earth has been to inform and empower ESRD patients and their families, because when you know better, you do better," said  Edwards. "I look forward to working with the board of directors and DPCs patient membership to further our mission of improving the quality of life for all dialysis patients."

Edwards was diagnosed with nephritis at an early age and began his journey as an end-stage renal disease (ESRD) patient at age 19. He received his first kidney transplant in 1999 and returned to hemodialysis six years later when the transplant failed. Edwards joined the board of directors in 2010 and previously served as a DPC patient ambassador for several years. He holds a dual B.B.A. in Finance and Marketing from J. Mack Robinson College of Business at Georgia State University and lives in Atlanta.

He succeeds former President Nancy Scott, who served as from April 2011. Her term ended prematurely after she received a kidney transplant last spring, as the DPC by-laws require the board president be a current dialysis patient. Scott will continue to serve on the board of directors and as the chair of the education committee.

"Nancy Scott has been a relentless advocate for her fellow kidney patients around the country and her contributions to our organization during her short tenure as president have been innumerable," said Hrant Jamgochian, DPC executive director. "While she will no longer serve as board president, we are excited about her dedication to our mission and her continued involvement with our organization."

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