Dialysis world news


Fatal allergic reactions to Omontys (peginesatide) trigger recall.
MedPage: All lots of the new anemia drug peginesatide (Omontys) have been recalled because of severe hypersensitivity reactions -- some fatal -- observed after the drug was approved last March. "No new or existing patients should receive Omontys," according to a statement from the two firms selling the drug, Affymax and Takeda. However, they stopped short of saying the product was being withdrawn from the market.

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Hemodialysis abstracts from upcoming Annual Dialysis Conference in Seattle.
HDI: Hemodialysis Abstracts from the 33rd Annual Dialysis Conference 24th Annual Symposium on Pediatric Dialysis Seattle, Washington, March 9-12, 2013

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New SARS coronavirus can spread like the common cold.
CTV News: Still, Thiel cautioned that just because the virus can easily infect human lung cells doesn't mean it has all the tools it would need to take off and spread widely among people. "We have shown that the airway cells can easily be infected. But this does not mean that the virus can easily be transmitted," he said. "I think this distinction is important."

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MMWR: Synthetic cannabinoid use and acute kidney injury.
CDC: Six of eight patients with a renal biopsy demonstrated acute tubular injury, and three of eight patients demonstrated features of acute interstitial nephritis. Kidney function recovery was apparent within 3 days of creatinine peak in most patients. However, five of the 16 patients required hemodialysis, and four patients received corticosteroids; none died. Other infectious, autoimmune, pharmacologic, or other toxic causes of AKI were not found.

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JASN: Full text of RCT comparing hemodiafiltration to hemodialysis.
JASN: (Maduell) The full text of the article is available at ths link. Conclusion: Compared with patients who continued on hemodialysis, those assigned to OL-HDF had a 30% lower risk of all-cause mortality (hazard ratio [HR], 0.70; 95% confidence interval [95% CI], 0.53–0.92; P=0.01), a 33% lower risk of cardiovascular mortality (HR, 0.67; 95% CI, 0.44–1.02; P=0.06), and a 55% lower risk of infection-related mortality (HR, 0.45; 95% CI, 0.21–0.96; P=0.03).

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