Dialysis world news


Warm extracorporeal perfusion of liver for 24 hours leads to successful transplant.
Times of India: In a world's first, scientists from Oxford University and doctors from King's College Hospital have successfully "kept alive" a donated human liver outside a human being and then successfully transplanted it into a patient in need of a new liver.

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New Handbook of Nephrology title available from LWW.
Lippincott Williams and Wilkins: The Handbook of Nephrology offers an analytical yet understandable overview of nephrology — with an emphasis on principles and pathophysiology. Written in a clear, outline format, this handbook provides learning strategies and content not found in other books. This pocket-sized book offers medical students, interns, and residents a concise introduction to the field. Primary care physicians, internists, surgeons, nurse practitioners, pharmacists, and physician assistants will also find this book useful.

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Niacin drug plus antiflushing compound had substantial side effects.
Reuters: But Dr. Steven Nissen, head of cardiology at Cleveland Clinic, had some serious criticism about the study's design, execution and conclusions, and was not prepared to write off niacin therapy just yet for patients with very low HDL levels.

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Mice cloned sequentially up to 25 times with no decrease in life span.
Science Daily: To prevent possible epigenetic changes, or modifications to DNA function that do not involve a change in the DNA itself, Wakayama and his team added trichostatin, a histone deacetylase inhibitor, to the cell culture medium. Using this technique, they increased cloning efficiency by up to 6-fold.

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New study validates anti-aging effects of resveratrol.
Science Daily: "This was the killer experiment," said Sinclair. "There is no rational alternative explanation other than resveratrol directly activates SIRT1 in cells. Now that we know the exact location on SIRT1 where and how resveratrol works, we can engineer even better molecules that more precisely and effectively trigger the effects of resveratrol."

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