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Treating Oligometastatic Renal Cell Carcinoma - OncLive

The management of an oligometastatic recurrence represents a challenging area in the treatment of patients with renal cell carcinoma (RCC), with local options gaining broader acceptance. For patients with relatively slow growing oligometastatic disease there is an opportunity for surgical resection, explains Eric Jonasch, MD.

Newer technologies, such as focused-beam stereotactic radiosurgery, can be used in various parts of the body, especially the brain, to treat oligometastatic disease, notes Thomas E. Hutson, DO, PharmD. Theories supporting the abscopal effect have suggested that administering radiation to one area results in tumor necrosis and subsequent control of cancer elsewhere by the immune system. However, randomized trials are still needed to prove this connection, notes David F. McDermott, MD.

While local approaches are effective for some patients, they may not be appropriate in every situation. Sarcomatoid RCC tends to be more aggressive, especially when surgery is performed, and may not be optimally managed by surgical intervention. The healing factors from surgery may promote the growth of sarcomatoid lesions, notes Jonasch. Stereotactic radiosurgery is an ideal option for patients with oligometastatic brain metastases following systemic therapy, adds Jonasch.

The integration of surgical and radiation disciplines in the course of a patient’s disease is imperative if they have progression in the bone or brain, states McDermott. In this setting, tyrosine kinase inhibition is less effective. The appropriate integration of surgical approaches for metastatic disease late in the biology of an individual’s disease can have positive outcomes.

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Treating Oligometastatic Renal Cell Carcinoma - OncLive - OncLive

The management of an oligometastatic recurrence represents a challenging area in the treatment of patients with renal cell carcinoma (RCC), with local options gaining broader acceptance. For patients with relatively slow growing oligometastatic disease there is an opportunity for surgical resection, explains Eric Jonasch, MD.

Newer technologies, such as focused-beam stereotactic radiosurgery, can be used in various parts of the body, especially the brain, to treat oligometastatic disease, notes Thomas E. Hutson, DO, PharmD. Theories supporting the abscopal effect have suggested that administering radiation to one area results in tumor necrosis and subsequent control of cancer elsewhere by the immune system. However, randomized trials are still needed to prove this connection, notes David F. McDermott, MD.

While local approaches are effective for some patients, they may not be appropriate in every situation. Sarcomatoid RCC tends to be more aggressive, especially when surgery is performed, and may not be optimally managed by surgical intervention. The healing factors from surgery may promote the growth of sarcomatoid lesions, notes Jonasch. Stereotactic radiosurgery is an ideal option for patients with oligometastatic brain metastases following systemic therapy, adds Jonasch.

The integration of surgical and radiation disciplines in the course of a patient’s disease is imperative if they have progression in the bone or brain, states McDermott. In this setting, tyrosine kinase inhibition is less effective. The appropriate integration of surgical approaches for metastatic disease late in the biology of an individual’s disease can have positive outcomes.

...

 
South Bronx commercial hub will now include health and dialysis centers - New York Daily News
New York Daily News
Triangle Plaza Hub, the mixed-use office and retail facility replacing a municipal parking lot in the Melrose section of the South Bronx, will now include dialysis and health centers, the Daily News has learned. Healthcare provider Brightpoint Health

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South Bronx hub will now include health and dialysis centers - NY Daily News ... - New York Daily News

Triangle Plaza Hub, the mixed-use office and retail facility replacing a municipal parking lot in the Melrose section of the South Bronx, will now include dialysis and health centers, the Daily News has learned.

Healthcare provider Brightpoint Health and DaVita Dialysis Center have both inked deals to take a combined 24,900 square feet of space at the $35 million, 88,000-square-foot complex on E. 149th St., bringing it close to full occupancy, developer Triangle Equities said.

Other tenants such as Fine Fare Supermarket, Metropolitan College of New York, Vistasite Eye Care and Boston Market had already signed on to take space at the center.

"With our grand opening fast approaching, we're excited to finally bring the services and amenities of this community-centric development to a deserving area, which, we believe, will catalyze continued improvements," said Lester Petracca, president of Triangle.

Brightpoint Health will lease 16,000 square feet on the second floor, while DaVita Dialysis Center is taking 8,900 square feet of ground floor retail space.

The complex, slated to open this fall, is expected to give a boost to one of the busiest intersections in the Bronx.

Work on the project, which arose out of a partnership with the city, began in 2013.

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The World Market for Catheters (Urological, Intravenous, Cardiovascular ... - PR Newswire (press release)
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DUBLIN, July 24, 2015 /PRNewswire/ -- Research and Markets (http://www.researchandmarkets.com/research/krmqgg/the_world_market) has announced the addition of the "The World Market for Catheters (Urological, Intravenous, Cardiovascular Intervention, Angiography, Dialysis, PTCA, PICC, Oximetry and Surgical Catheters)" report to their offering.

Among the catheters used in urological applications are the Foley and the urethral catheters. Cardiovascular catheters find use in cardiac catheterization. Angiography catheters are used in cardiological diagnostics. Intravenous catheters are used if a person requires frequent or continuous injections of medications or fluids for nutritional support. A wound drain catheter is inserted while a patient is in the operating room receiving general anesthesia All of these catheters are included in this report. 

For many of these segments, company market share and regional breakout for US, Europe and Rest of World is provided. In addition to numbers that can be useful for business planning, the report provides analysis of the industry, including analysis of several important trends.

Increased life expectancy and subsequent aging of the global population play a key role in the rising demand for all types of medical catheters. Companies seeking opportunities in this medical device market will want to utilize Kalorama Information's World Market for Catheters. 

This report contains global market size and forecast to 2019 for the following types of catheters: 

  • Foley Catheters
  • Urethral Catheters
  • PTCA Catheters
  • Dialysis Catheters
  • Atherectomy Catheters
  • Ablation Catheters
  • Cardiac Angiography Catheters
  • Peripheral Angiography Catheters
  • Implantable Ports
  • Central Venous Catheters
  • Peripheral Insertion Catheters
  • Peripherally Inserted Central Catheters
  • Peripheral Insertion Midline Catheters
  • Oximetry Catheters
  • Thermodilution Catheters
  • Suction Catheters
  • Wound Drainage Catheters

Trends discussed in this report include the following:

  • Infection and Control
  • Vascular
  • Urinary
  • Catheter Intervention Trends
  • Catheter Malfunction
  • Antimicrobial Lock Solutions
  • Stroke Treatment
  • MRI Catheters
  • Sinus Balloon Catheter
  • Interventional Radiology
  • Heart Patch
  • PFO
  • New And Alternative Materials
  • Antiseptic-Coated Catheters

Company profiles are included, with profiles of the following companies:

  • Abbott Laboratories
  • Angio Dynamics
  • Atrium Medical
  • Bactiguard Ab
  • C.R. Bard
  • Becton Dickinson
  • Boston Scientific
  • B. Braun Melsungen
  • Cardinal Health
  • Carmeda
  • Cook Group
  • Catheter Research Inc.
  • Covidien
  • Edwards Lifesciences
  • Greatbatch Medical
  • Johnson &Johnson
  • Flexicath
  • Hansen Medical
  • Iapyx Medical
  • Integra Lifesciences Holdings
  • Irvine Scientific
  • Medtronic
  • Medcomp
  • Siemens Medical Solutions
  • Smiths Medical
  • St.Jude Medical
  • Teleflex Medical Company
  • Terumo
  • Vascular Solutions
  • Vesta Inc.
  • Volcano Corp.
  • Zimmer Holdings

For more information visit http://www.researchandmarkets.com/research/krmqgg/the_world_market

Media Contact:

Laura Wood, +353-1-481-1716, This e-mail address is being protected from spambots. You need JavaScript enabled to view it

 

SOURCE Research and Markets

RELATED LINKS
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